Friday, October 3

10:00-10:15

Welcome

Session 1

Gene Mutations

CEBPA: Biology and Prognostic significance

H. Dombret

NPM1:Biology and prognostic significance

B. Falini

NPM1:Prognostic significance

K. Döhner

NPM1:Therapeutic targeting

R. Schlenk

FLT3: Prognostic significance

R. Gale

FLT3: Prognostic significance ˆ allelic ratio

C. Thiede

FLT3: Therapeutic targeting

D. Small

Round Table

Session 2

Gene Mutations (continued)

KIT mutations

P. Paschka

WT1 mutations

J. Fitzgibbon

MLL-PTD

S. Whitman

AML1 mutations

S. Schnittger

Round Table

Session 3

Prognostic Impact of Cytogenetics: New Insights Revisited

Individual cytogenetic markers

C. Bloomfield

Individual cytogenetic markers

B. Lowenberg

Individual cytogenetic markers

D. Grimwade

Round Table

Saturday, October 4

Session 4

SNP Analyses

SNP in AML

J. Downing

SNP in AML

B. Young

SNP in AML

N.N.

Round Table

Session 5

Gene Expression

BAALC: Biology and prognostic significance

C. Baldus

EVI-1: Biology and prognostic significance

R. Delwel

ERG: Biology and prognostic significance

G. Marcucci

MN1: Biology and prognostic significance

A. Ganser

Round Table

Session 6

High Throughput Technologies

Gene expression profilling

P. Valk

Gene expression profilling

L. Bullinger

Gene expression profilling

T. Haferlach

Gene expression profilling

M. Radmacher

MicroRNA profiling

T. Golub

MicroRNA profiling

M. Jongen

Round Table

Sunday, October 5

Session 7

Towards an Integrated Prognostic Algorithm

Considerations about a composite prognostic score

S. Amadori

Considerations about a composite prognostic score

F. Appelbaum

Considerations about a composite prognostic score

C. Bloomfield

Considerations about a composite prognostic score

A. Burnett

Considerations about a composite prognostic score

H. Dohner

Considerations about a composite prognostic score

H. Dombret

Considerations about a composite prognostic score

E. Estey

Considerations about a composite prognostic score

B. Lowenberg

Considerations about a composite prognostic score

T. Naoe

Considerations about a composite prognostic score

J. Sierra

Considerations about a composite prognostic score

M. Tallman

Open forum: Conclusions, Recommendations